AZCA is a business and shopping square area limited to the East by Paseo de la Castellana, the main North-South axis of Madrid where all the financial activity is concentrated; To the South is Raimundo Fernández Villaverde street -which, in connection with other streets and avenues, divides Madrid diagonally via flyovers and underpasses.

Torre Picasso benefits from AZCA's extraordinary public transportation connections. The area is reached and accessed by 1 train station, several bus lines and 2 metro stations. Also, there are direct connections to main train stations Atocha (High Speed) and Chamartín, as well as to Barajas airport.

At the foot of the building, there is an exclusive zone assigned for the landing of passengers from taxis and private vehicles.

The main entrance is accessible from Paseo de la Castellana and through Plaza Ruiz Picasso -as well as from pedestrian walks exiting from General Peron Avenue and Orense Street. All these provide convenient communications between Torre Picasso and its surroundings.